ABCA9 Polyclonal Antibody
Catalogue Numbers: BS61300-50, BS61300-100
Sizes: 50µl, 100µl
Alternative Name: ATP-binding cassette sub-family A member 9; ABCA9
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q8IUA7
Host: Rabbit
Reactivity: Human, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: ABCA9 (ATP-binding cassette, sub-family A (ABC1), member 9) is a 1,624 amino acid protein belonging to the ABC transporter superfamily and the ABCA family. The ABC1 subfamily is the only major ABC subfamily exclusive to multicellular eukaryotes. Ubiquitously expressed, with high expression in heart, brain and fetal tissues, ABCA9 is a multi-pass membrane protein that contains two ABC transporter domains and exists as five alternatively spliced isoforms. ABCA9 exhibits membrane subcellular localization and may play a role in monocyte differentiation and lipid homeostasis. ABCA9 is up-regulated during monocyte differentiation into macrophages and down-regulated by cholesterol loading of macrophages. Spanning 85 kb, ABCA9 contains 39 exons, with a non-coding first exon. ABCA9 is one of five ABC1 family members that maps to human chromosome 17q24.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ABCA9 polyclonal antibody detects endogenous levels of ABCA9 protein.
Bioworld Molecular Weight: ~ 163 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of ABCA9 polyclonal antibody at 1:500 dilution
Line1:HEK293T whole cell lysate
Line2:H9C2 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human ABCA9.
Conjugate: Unconjugated
Modification: Unmodified