ABCG1 Polyclonal Antibody
Catalogue Numbers: BS5596-50, BS5596-100
Sizes: 50µl, 100µl
Alternative Name: ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; White protein homolog; ABC8; WHT1
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P45844
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: ABCG1 (also designated ABC8 or human white gene), a member of the evolutionary conserved family of ATP-binding cassette (ABC) transporters, exhibits high homology with the Drosophila white gene. ABC transporters couple the energy of ATP hydrolysis to the translocation of various molecules across biological membranes. These proteins contain characteristic ATP-binding domains and transmembrane domains which form a channel-like structure for transport. ABCG1 functions to regulate cholesterol and phospholipid transport in macrophages. ABCG1 is highly expressed in several tissues, including brain, spleen, lung and placenta, and has been localized to the cell surface and intracellular compartments of cholesterol-laden macrophages.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ABCG1 polyclonal antibody detects endogenous levels of ABCG1 protein.
Bioworld Molecular Weight: ~ 110 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of ABCG1 polyclonal antibody at 1:500 dilution
Lane 1: Jurkat cell lysate
Lane 2: Mouse liver tissue lysate
Lane 3: Rat liver tissue lysate
Immunogen: Synthetic peptide, corresponding to amino acids 633-678 of Human ABCG1.
Conjugate: Unconjugated
Modification: Unmodified