Product Description

ABHD4 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21557-50, RA21557-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: caution:Thr-291 is present instead of the conserved His which is expected to be an active site residue., function:Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine., similarity:Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.,

Reactivity: Human, Mouse

Host: Rabbit

Applications: IHC-p, IF (paraffin section), ELISA

Alternate Names: ABHD4, Abhydrolase domain-containing protein 4, Alpha/beta-hydrolase 4, Lyso-N-acylphosphatidylethanolamine lipase

Clonality: Polyclonal

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Storage: -20°C/1 year

Human Gene ID: 63874

Human SwissProt Number: Q8TB40

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only