ABHD4 rabbit pAb - ES7138

ABHD4 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7138-50, ES7138-100

Citations, Manuals and MSDS Available upon request.

Background: caution:Thr-291 is present instead of the conserved His which is expected to be an active site residue., function:Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine., similarity:Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.,

Alternate Name: ABHD4; Abhydrolase domain-containing protein 4; Alpha/beta-hydrolase 4; Lyso-N-acylphosphatidylethanolamine lipase

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human ABHD4. AA range:251-300

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 63874

Human SWISS Prot NO: Q8TB40

Subcellular Location: endoplasmic reticulum membrane, lipid particle,

Research Use Only