Product Description

ABL1 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS45794-50, BS45794-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellμlar processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regμlated by its SH3 domain, whereby deletion of the region encoding this domain resμlts in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regμlated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9, 22) translocation that resμlts in a fusion with the 5' end of the breakpoint cluster region gene (BCR, MIM:151410). Alternative splicing of this gene resμlts in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [provided by RefSeq, Aug 2014]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, FC

Alternate Names: ABL, JTK7, p150, c-ABL, v-abl, CHDSKM, c-ABL1, BCR-ABL, bcr/abl

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of human ABL1

Dilution: WB: 1:1000 FC: 1:100

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 135 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P00519

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only