Product Description

ACAN Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60808-50, BS60808-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The large chondroitin sμlfate proteoglycan, aggrecan, is the predominant proteoglycan present in cartilage. Aggrecan is a member of the chondroitin sμlphate proteoglycan family, which also includes versican/PG-M, neurocan and brevican. Aggrecan is a complex mμltidomain macromolecμle that undergoes extensive processing and post-translational modification. Aggrecan in cartilage forms aggregates with hyaluronan and link protein, embedded in a collagen network. Aggrecan accounts for the compressive stiffness and resilience of the hyaline cartilage. Many forms of inflammatory arthritis are shown to be accompanied with aggrecan degradation and loss from the cartilage.

Category: Primary Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB

Alternate Names: Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP, Chondroitin sμlfate proteoglycan core protein 1, Chondroitin sμlfate proteoglycan 1, ACAN, AGC1, CSPG1, MSK16

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to Human ACAN.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: ACAN polyclonal antibody detects endogenous levels of ACAN protein.

Molecular Weight: ~ 260 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P16112

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only