Acetyl-EPAS-1 (K385) Polyclonal Antibody - BT-AP00162

Acetyl-EPAS-1 (K385) Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00162-20, BT-AP00162-50, BT-AP00162-100

Citations, Manuals and MSDS Available upon request.

Background: EPAS1 (endothelial PAS domain protein 1) encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in EPAS1 are associated with erythrocytosis familial type 4.

Research Areas: Cardiovascular; Metabolism

Target Protein: K385

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Acetyl-EPAS-1 (K385) Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 96459

UniProt Accession: Human: Q99814; Mouse: P97481; Rat: Q9JHS1

Synonyms: endothelial PAS domain protein 1

GeneID: Human: 2034

Research Use Only