Acetyl-Histone H3 (K9) Monoclonal Antibody (2E7) - BT-MCA0131

Acetyl-Histone H3 (K9) Monoclonal Antibody (2E7)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0131-20, BT-MCA0131-50, BT-MCA0131-100

Citations, Manuals and MSDS Available upon request.

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails| instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Research Areas: Epigenetics and nuclear signaling

Target Protein: HIST1H3A

Applications: IHC-p, IF

Reactivity: Human,Rat,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: HIST1H3A

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P68431; Mouse: P68433; Rat: Q6LED0

Synonyms: HIST1H3A; H3k9AC

GeneID: Human: 8290

Research Use Only