Product Description

Acetyl-p53 (Lys370) Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB10486-50, MB10486-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Tumor protein p53, a nuclear protein, plays an essential role in the regμlation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ICC/IF, IP

Alternate Names: P53, BCC7, LFS1, TRP53

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Acetylated

Immunogen: A synthetic acetyl-peptide corresponding to residues surrounding Lys370 of human p53

Dilution: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 44 kDa, Observed MW: 53 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P04637

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Research Use Only