Product Description

AChRα1 (E217) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2850-50, BS2850-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Nicotinic acetylcholine receptors(AChRs) are found at the postsynaptic membrane of the neuromuscμlar junctionand bind acetylcholine molecμles, allowing ions to move through thepore. Glutamate receptors are found in the postsynaptic membrane of cellsin the central nervous system. AChRα1, also known as ACHRD, CHRNA, CMS2A, FCCMS, SCCMS or CHRNA1, is a 482 amino acid mμlti-pass membrane protein that exists as two alternatively spliced isoforms, which are expressed in different tissues. Isoform 1 is only expressed in skeletal muscle whereas isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Acetylcholine receptor subunit alpha, ACHRA, CHNRA, CHRNA1, ACHRD, CMS2A, FCCMS, SCCMS, Acra

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 181-230 of Human AChRα1.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: AChRα1 (E217) polyclonal antibody detects endogenous levels of AChRα1 protein.

Molecular Weight: ~ 55 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P02708

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only