Product Description

AChRα5 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS6567-50, BS6567-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscμlar junction and bind acetylcholine molecμles, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChRα5, also known as LNCR2 or CHRNA5 (cholinergic receptor, nicotinic, alpha 5), is a 468 amino acid mμlti-pass membrane protein belonging to the ligand-gated ionic channel family and is involved in the mediation of fast signal transmission at synapses.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Alternate Names: ACHA5, alpha polypeptide 5, cholinergic receptor, Cholinergic receptor neuronal nicotinic alpha polypeptide 5, Cholinergic receptor nicotinic alpha 5, Cholinergic receptor nicotinic alpha polypeptide 5, CHRNA 5, CHRNA5, LNCR2, NACHRA 5, NACHRA5, Neuronal acetylcholine receptor subunit alpha 5, Neuronal acetylcholine receptor subunit alpha-5, Neuronal nicotinic acetylcholine receptor alpha 5 subunit, Neuronal nicotinic acetylcholine receptor, alpha5 subunit, nicotinic,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human AChRα5.

Dilution: WB 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: AChRα5 polyclonal antibody detects endogenous levels of AChRα5 protein.

Molecular Weight: ~ 53 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P30532

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only