ACINU Polyclonal Antibody - BT-AP14097

ACINU Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14097-20, BT-AP14097-50, BT-AP14097-100

Citations, Manuals and MSDS Available upon request.

Background: Apoptosis is defined by several morphologic nuclear changes| including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3| without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs| as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Research Areas: Cancer; Cell biology; Epigenetics and nuclear signaling; Metabolism

Target Protein: ACIN1

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Apoptotic chromatin condensation inducer in the nucleus

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9UKV3; Mouse: Q9JIX8

Synonyms: Apoptotic chromatin condensation inducer in the nucleus;Acinus

GeneID: Human: 22985

Research Use Only