Ack1 (Phospho-Tyr857+Tyr858) Rabbit Polyclonal Antibody - RA36874

Ack1 (Phospho-Tyr857+Tyr858) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36874-50, RA36874-100

Citations, Manuals and MSDS Available upon request.

Background: tyrosine kinase non receptor 2 (TNK2) Homo sapiens This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP) -stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, and 0.190% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000

Alternative Names: Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 10188

SWISS: Q07912

Source: Rabbit

Research Use Only