ACL6B Polyclonal Antibody - BT-AP14102

ACL6B Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14102-20, BT-AP14102-50, BT-AP14102-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold| which is an ATP-binding cleft| as a common feature. The ARPs are involved in diverse cellular processes| including vesicular transport| spindle orientation| nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals| which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin| specifically in the brain. Alternative splicing results in multiple transcript variants.

Research Areas: Epigenetics and nuclear signaling; Neuroscience; Stem cells

Target Protein: ACTL6B

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Actin-like protein 6B

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O94805; Mouse: Q99MR0; Rat: P86173

Synonyms: Actin-like protein 6B;53 kDa BRG1-associated factor B;Actin-related protein Baf53b;ArpNalpha;BRG1-associated factor 53B;BAF53B

GeneID: Human: 51412

Research Use Only