Acrosin rabbit pAb - ES1000

Acrosin rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1000-50, ES1000-100

Citations, Manuals and MSDS Available upon request.

Background: Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. [provided by RefSeq, Jul 2008],

Alternate Name: ACR; ACRS; Acrosin

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from Acrosin . at AA range: 40-120

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 45kD

Human Gene ID: 49

Human SWISS Prot NO: P10323

Subcellular Location: acrosomal vesicle, extracellular region, nucleus, Golgi-associated vesicle, acrosomal matrix, protein complex,

Research Use Only