Actin-Alpha cardiac muscle Polyclonal Antibody - BT-AP00219

Actin-Alpha cardiac muscle Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00219-20, BT-AP00219-50, BT-AP00219-100

Citations, Manuals and MSDS Available upon request.

Background: Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. Actin alpha cardiac muscle 1 encoded by ACTC1 belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

Research Areas: Signal Transduction; Cardiovascular

Target Protein: ACTC1

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Actin-alpha cardiac muscle Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 42019

UniProt Accession: Human: P68032; Mouse: P68033; Rat: P68035

Synonyms: ACTC1; ACTC; Actin, alpha cardiac muscle 1; Alpha-cardiac actin

GeneID: Human: 70; Mouse: 11464; Rat: 29275

Research Use Only