Actin-Alpha/Gamma Polyclonal Antibody - BT-AP00220

Actin-Alpha/Gamma Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00220-20, BT-AP00220-50, BT-AP00220-100

Citations, Manuals and MSDS Available upon request.

Background: The product encoded by ACTA1 (actin, alpha 1, skeletal muscle) belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in ACTA1 cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Research Areas: Others

Target Protein: ACTC1

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Actin-alpha/gamma Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 41737/41793

UniProt Accession: Human: P68032/P63261/P63267/P68133; Rat: P68035/P63259/P63269/P68136

Synonyms: ACTC1; ACTC; Actin; alpha cardiac muscle 1; Alpha-cardiac actin; ACTG1; ACTB; ACTG; Actin, cytoplasmic 2; Gamma-actin; ACTG2; ACTA3; ACTL3; ACTSG; Actin, gamma-enteric smooth muscle; Alpha-actin-3; G

GeneID: Human: 58/70/71/72; Mouse: 11464/11465/11468/11459; Rat: 29275/100361457/25365/29437

Research Use Only