Product Description

Actinin-Alpha3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00218-20, BT-AP00218-50, BT-AP00218-100

Citations, Manuals and MSDS Available upon request.

Background: ACTN3 encodes a member of the alpha-actin binding protein gene family. Actinin alpha 3 (gene/pseudogene) is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of ACTN3 is associated with elite athlete status.

Research Areas: Signal Transduction

Target Protein: ACTN3

Applications: WB, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Actinin-alpha3 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 103294

UniProt Accession: Human: Q08043; Mouse: O88990

Synonyms: ACTN3; Alpha-actinin-3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein

GeneID: Human: 89; Mouse: 11474

Research Use Only