ACTL6A Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90026-50, BS90026-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: O96019(Human) Q9Z2N8(Mouse)
Host: Rabbit
Reactivity: Human, Mouse
Applications: WB, ICC IF, IHC, IP,
All Applications: WB:1:500-1:2,000
ICC/IF:1:50-1:100
IHC:1:50-1:100
IP:1:10-1:50
Background: ACTL6A also named BAF53. The SWI/SNF complex regulates gene expression via ATP-dependent chromatin remodeling. Brm (SNF2-a), Brg-1 (SNF2-b), Ini1 (integrase interactor 1, SNF5), BAF53 (ARPnβ), BAF57, BAF155 (SRG3), and BAF170 make up the functional core. BAF53 homologues from yeast to humans contain a conserved N-terminal motif, which contains residues at serine 2 and tyrosine 6, which play important roles in BAF53 activity. The BAF53 protein shuttles between the nucleus and cytoplasm. BAF53 also forms a complex with TIP49 and TIP48, which mediates c-Myc oncogenic activity.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: ACTL6A polyclonal antibody detects endogenous levels of ACTL6A protein.
Bioworld Molecular Weight: 47 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of ACTL6A on Jurkat cell(1) and mouse brain tissue(2) lysate using anti-ACTL6A antibody at 1/500 dilution., ICC staining ACTL6A in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: BAF53A, ACTL6A, BAF53, BAF53A, INO80K, 53 kDa BRG1 associated factor A, 53 kDa BRG1-associated factor A, ACL6A, Actin like 6A, Actin like protein 6A, Actin related protein 4, Actin related protein, Actin related protein Baf53a, Actin-like protein 6A, Actin-related protein Baf53a, ACTL 6, ACTL 6A, ACTL6, ACTL6A, Arp4, ARPN BETA, ArpNbeta, BAF 53A, BAF complex 53 kDa subunit, BAF53, BAF53A, BRG1 associated factor, BRG1-associated factor 53A, hArpN beta, INO80 complex subunit K, INO80K, MGC5382,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodified