ACTR-IB Polyclonal Antibody - BT-AP00223

ACTR-IB Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00223-20, BT-AP00223-50, BT-AP00223-100

Citations, Manuals and MSDS Available upon request.

Background: ACVR1B encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in ACVR1B are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.

Research Areas: Signal Transduction; Stem Cells

Target Protein: ACVR1B

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: ACTR-IB Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 56807

UniProt Accession: Human: P36896; Mouse: Q61271; Rat: P80202

Synonyms: ACVR1B; ACVRLK4; ALK4; Activin receptor type-1B; Activin receptor type IB; ACTR-IB; Activin receptor-like kinase 4; ALK-4; Serine/threonine-protein kinase receptor R2; SKR2

GeneID: Human: 91; Mouse: 11479; Rat: 29381

Research Use Only