ACTR-IC Polyclonal Antibody - BT-AP00224

ACTR-IC Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00224-20, BT-AP00224-50, BT-AP00224-100

Citations, Manuals and MSDS Available upon request.

Background: ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al. 2001 [PubMed 12063393]).

Research Areas: Signal Transduction

Target Protein: ACVR1C

Applications: IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: ACTR-IC Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 54871

UniProt Accession: Human: Q8NER5; Mouse: Q8K348; Rat: P70539

Synonyms: ACVR1C; ALK7; Activin receptor type-1C; Activin receptor type IC; ACTR-IC; Activin receptor-like kinase 7; ALK-7

GeneID: Human: 130399; Mouse: 269275; Rat: 245921

Research Use Only