ADA15 Polyclonal Antibody - BT-AP14126

ADA15 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14126-20, BT-AP14126-50, BT-AP14126-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain| a disintegrin-like domain| as well as a EGF-like domain. Through its disintegrin-like domain| this protein specifically interacts with the integrin beta chain| beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner| suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Research Areas: Signal transduction; Cancer; Cell biology

Target Protein: ADAM15

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Disintegrin and metalloproteinase domain-containing protein 15

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q13444; Mouse: O88839; Rat: Q9QYV0

Synonyms: Disintegrin and metalloproteinase domain-containing protein 15;ADAM 15;EC 3.4.24.-;Metalloprotease RGD disintegrin protein;Metalloproteinase-like; disintegrin-like; and cysteine-rich protein 15

GeneID: Human: 8751

Research Use Only