ADA22 Polyclonal Antibody - BT-AP14128

ADA22 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14128-20, BT-AP14128-50, BT-AP14128-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins| and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions| including fertilization| muscle development| and neurogenesis. Unlike other members of the ADAM protein family| the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice| it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.

Research Areas: Signal transduction; Cell biology

Target Protein: ADAM22

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Disintegrin and metalloproteinase domain-containing protein 22

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9P0K1; Mouse: Q9R1V6

Synonyms: Disintegrin and metalloproteinase domain-containing protein 22;ADAM 22;Metalloproteinase-disintegrin ADAM22-3;Metalloproteinase-like; disintegrin-like; and cysteine-rich protein 2

GeneID: Human: 53616

Research Use Only