Product Description

ADAM17 Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40435-50, BS40435-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: TACE is responsible for the shedding of EGFR ligands such as amphiregμlin and TNF-α. Some tumors have hyperactivated EGFR due to upregμlated TNF-α production and upregμlated TACE, making TACE a potential target for drug development. TACE activates Notch in a ligand-independent manner and has been shown to play a role in the development of the Drosophila nervous system.

Category: Primary Antibody

Reactivity: Human Mouse Rat

Host: Rabbit

Applications: WB, ICC/IF, IP, FC

Alternate Names: CD156b, ADAM17, CSVP, TACE,

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: A synthesized peptide derived from human ADAM17

Dilution: WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:100

Purification: Affinity-chromatography

Specificity: ADAM17 Antibody detects endogenous levels of total ADAM17

Molecular Weight: 100kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P78536

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only