ADAMTS-1 Polyclonal Antibody - BT-AP00243

ADAMTS-1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00243-20, BT-AP00243-50, BT-AP00243-100

Citations, Manuals and MSDS Available upon request.

Background: ADAMTS1 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. ADAM metallopeptidase with thrombospondin type 1 motif 1 encoded by ADAMTS1 contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of ADAMTS1 may be associated with various inflammatory processes as well as development of cancer cachexia. ADAMTS1 is likely to be necessary for normal growth, fertility, and organ morphology and function.

Research Areas: Cardiovascular; Tags and Cell Markers

Target Protein: ADAMTS1

Applications: WB, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: ADAMTS-1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 105358

UniProt Accession: Human: Q9UHI8; Mouse: P97857

Synonyms: ADAMTS1; KIAA1346; METH1; A disintegrin and metalloproteinase with thrombospondin motifs 1; ADAM-TS 1; ADAM-TS1; ADAMTS-1; METH-1

GeneID: Human: 9510

Research Use Only