Product Description

ADAMTS17  Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61126-50, BS61126-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ADAMTS (a disintegrin and metalloproteinase domain with Thrombospondin type-1 modμles) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer. ADAMTS protein family members contain an N-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a C-terminus that contains a varying number of Thrombospondin type-1 (TSP-1) motifs. ADAMTS-17 (ADAM metallopeptidase with Thrombospondin type-1 motif, 17) is a 1, 095 amino acid secreted protein that belongs to the ADAMTS family. Expressed in liver, prostate, brain and in fetal lung, ADAMTS-17 has seven N-glycosylation sites and shares 56% sequence identity with a related family member, ADAMTS-19. ADAMTS-17 has a conserved cysteine residue in its cysteine-switch motif that, when bound to one zinc ion, inhibits the enzymatic activity of the protein.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: A disintegrin and metalloproteinase with thrombospondin motifs 17, ADAM-TS 17, ADAM-TS17, ADAMTS-17, ADAMTS17

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to Human ADAMTS17.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: ADAMTS17 polyclonal antibody detects endogenous levels of ADAMTS17 protein.

Molecular Weight: ~ 121 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8TE56

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only