ADAMTS4 Monoclonal Antibody
Catalogue Numbers: MB66736-50, MB66736-100
Sizes: 50µl, 100µl
Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Swiss-Prot: O75173
Host: Mouse
Reactivity: Human
Applications: WB
All Applications: WB (1/500 - 1/4000)
Background: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
Purification and Purity: This antibody is purified through a protein G column.
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Recognizes endogenous levels of ADAMTS4 protein.
Extra Notes: Western blot analysis of ADAMTS4 expression in recombinant protein (A) whole cell lysates.
Bioworld Molecular Weight: ~ 90 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: KIAA0688; A disintegrin and metalloproteinase with thrombospondin motifs 4; ADAM-TS 4; ADAM-TS4; ADAMTS-4; ADMP-1; Aggrecanase-1
Immunogen: Recombinant fusion protein of human ADAMTS4. The exact sequence is proprietary.
Conjugate: Unconjugated
Modification: Unmodified