Product Description

Adenosine Deaminase Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66755-50, MB66755-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Adenosine deaminase is an enzyme that is present in most tissues. It exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellμlar adenosine, which is toxic for lymphocytes. Adenosine deaminase also effects co-stimμlatory signals in T cells via interactions with CD26. Deficiency of adenosine deaminase has been shown to lead to immunodeficiency diseases such as SCID (severe combined immunodeficiency disease) and has been associated with hereditary hemolytic anemia, a disease in which adenosine deaminase levels are elevated fifty to seventy fold.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: ADA1, Adenosine deaminase, Adenosine aminohydrolase

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Adenosine Deaminase. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of Adenosine Deaminase protein.

Molecular Weight: ~ 39 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P00813

Product: Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only