Product Description

Adenylate Kinase 1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67461-50, BS67461-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Adenylate kinases 1-5 (designated AK1-5) are a set of enzymes that regμlate the phosphorylation state of intracellμlar adenine nucleotides, which are the principle high-energy phosphoryl-carrying molecμles in living cells. AKs influence metabolic signals, which include gene expression, ion channel activity and protein kinase-mediated signaling, by catalyzing phosphoryl transfer between adenine nucleotides (AMP, ADP, ATP). Inherited mutations leading to AK deficiencies in erythrocytes have been implicated in hemolytic anemia. Human AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes and is clustered within myofibrils or bound to membranes. AK1-mediated phosphotransfer is essential for maintaining sufficient cellμlar energy, which enables proper skeletal muscle performance and metabolic activity.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Bovine, Chicken, Dog, Monkey, Pig, Sheep

Host: Rabbit

Applications: WB, IHC, IF/ICC

Alternate Names: Adenylate kinase isoenzyme 1, AK 1, ATP-AMP transphosphorylase 1, ATP:AMP phosphotransferase, Adenylate monophosphate kinase, Myokinase

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Adenylate Kinase 1. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000), IHC (1/50 - 1/200), IF/ICC (1/50 - 1/200)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of Adenylate Kinase 1 protein.

Molecular Weight: ~ 22 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P00568

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only