Product Description

ADH7 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5600-50, BS5600-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ADH7 (alcohol dehydrogenase 7 (class IV), µ or σ polypeptide), is a 386 amino acid protein belonging to the zinc-containing alcohol dehydrogenase family and the class-IV subfamily. Seven different human ADH isozymes exist: three belong to class-I: α, β and γ, one to class-II: π, one to class-III: χ, one to class-IV: ADH7, and one to class-V: ADH6. Encoded by a gene that maps to human chromosome 4q23, ADH7 localizes to the cytoplasm and is preferentially expressed in stomach, but, unlike other family members, is absent from liver. ADH7 is a homodimer that binds two zinc ions per subunit and contains nine exons. ADH7 participates in the synthesis of retinoic acid, a hormone important for cellμlar differentiation. Variations in ADH7 may be associated with alcohol dependence. ADH7 may also play a role in protection against aerodigestive tract cancer.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Alcohol dehydrogenase class 4 mu/sigma chain, Alcohol dehydrogenase class IV mu/sigma chain, Gastric alcohol dehydrogenase, Retinol dehydrogenase, ADH7

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human ADH7.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: ADH7 polyclonal antibody detects endogenous levels of ADH7 protein.

Molecular Weight: ~ 40 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P40394

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only