ADHX Polyclonal Antibody - BT-AP06085

ADHX Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06085-20, BT-AP06085-50, BT-AP06085-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates| including ethanol| retinol| other aliphatic alcohols| hydroxysteroids| and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation| but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione| a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde| a potent irritant and sensitizing agent that causes lacrymation| rhinitis| pharyngitis| and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

Research Areas: Signal transduction; Metabolism

Target Protein: ADH5

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Alcohol dehydrogenase class-3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P11766; Mouse: P28474; Rat: P12711

Synonyms: Alcohol dehydrogenase class-3;EC 1.1.1.1;Alcohol dehydrogenase 5;Alcohol dehydrogenase class chi chain;Alcohol dehydrogenase class-III;Glutathione-dependent formaldehyde dehydrogenase;FALDH

GeneID: Human: 128

Research Use Only