ADK (E6) Polyclonal Antibody
Catalogue Numbers:BS2021-50, BS2021-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P55263
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: IHC, IF
All Applications: IHC: 1:50~1:200
IF: 1:50~1:200
Background: Adenosine kinase (ATP:adenosine 5 prime phosphotransferase) is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma phosphate from ATP to adenosine, thereby serving as a potentially important regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of ADK could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as antiinflammatory agents. The encoded protein does not present any sequence similarities to other well characterized mammalian nucleoside kinases. In contrast, 2 regions were identified with significant sequence identity to microbial ribokinase and fructokinases and a bacterial inosine/guanosine kinase. Thus, ADK is a structurally distinct mammalian nucleoside kinase that appears to be akin to sugar kinases of microbial origin.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Bioworld Molecular Weight: ~ 40 kDa
Specificity: ADK (E6) polyclonal antibody detects endogenous levels of ADK protein.
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: Adenosine kinase; Short name=AK; Adenosine 5'-phosphotransferase; ADK
Immunogen: Recombinant full length Human ADK.
Conjugate: Unconjugated
Modification: Unmodified