Product Description

ADNP  Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2362-50, BS2362-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Activity-dependent neuroprotector (ADNP), also designated activity-dependent neuroprotective protein, is a nuclear protein that functions as a putative transcription factor and may participate in normal growth and cancer proliferation. ADNP is a highly conserved vasoactive intestinal peptide (VIP) responsive gene that is expressed profusely in the brain (primarily cerebellum and cortex regions) and is crucial for brain formation and embryonic development. ADNP is also highly expressed in kidney, placenta, heart, skeletal muscle, breast, and colon cancer tissues. Studies indicate that neuroprotection by subpicomolar PACAP38 might be mediated partially by expression of ADNP. A correlation between brain injuries and elevated ADNP levels indicates a potential involvement of ADNP in an endogenous compensatory mechanism.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Activity-dependent neuroprotector homeobox protein, Activity-dependent neuroprotective protein, ADNP, ADNP1, KIAA0784

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding Human ADNP.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: ADNP polyclonal antibody detects endogenous levels of ADNP protein.

Molecular Weight: ~ 123 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9H2P0

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only