Product Description

ADRA1D Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61380-50, BS61380-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: α1D-adrenergicreceptors(α1D-ARs)couple to Gq/11 and participate directly in sympatheticregμlation ofsystemic blood pressure byvasoconstriction. α1D-AR can form hetero-oligomers with α1B receptors. α1D-AR transcripts are abundant in prostate and aorta. α1A adrenergicreceptors(α1A-ARs) mediate actionsin the sympathetic nervoussystem through the binding of the catecholamines, epinephrine and norepinephrine. α1A-adrenergic receptors couple to Gq/11 and regμlate blood pressure due to changesin vascμlar tone and cardiac output. Alternative splicing of this gene generatesfour isoforms with distinct C-termini, and the different expression profile of these subtypes produces distinct patterns of activation. α1A-AR transcripts are abundant in heart, brain, liver, and prostate. α1A-AR transcriptsizes of 6.0, 4.0, 3.0, and 2.0 kb have been detected in liver. α1A-AR transcriptsizes of 6.0, 4.0 and 3.0 kb transcripts have been detected in heart, and 6.0 kb and 4.0 kb transcripts have been detected in prostate.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: Alpha-1D adrenergic receptor, Alpha-1A adrenergic receptor, Alpha-1D adrenoreceptor, Alpha-1D adrenoceptor, Alpha-adrenergic receptor 1a, ADRA1D, ADRA1A

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Synthetic peptide, corresponding to amino acids456-501 of Human ADRA1D

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: ADRA1D polyclonal antibody detects endogenous levels of ADRA1D protein.

Molecular Weight: ~ 60 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P25100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only