Adrenodoxin Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10502-50, MB10502-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P10109
Host: Rabbit
Reactivity: Human, Mouse
Applications: WB, IHC-P, IP,
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Background: Essential for the synthesis of various steroid hormones (PubMed:20547883, PubMed:21636783). Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis (PubMed:20547883, PubMed:21636783). Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage (PubMed:20547883, PubMed:21636783). Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons .
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 19 kDa; Observed MW: 14 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Adrenodoxin in 3T3 lysates using Adrenodoxin antibody., Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Adrenodoxin antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.
Alternative Name: ADX; FDX; LOH11CR1D
Immunogen: A synthetic peptide of human Adrenodoxin
Conjugate: Unconjugated
Modification: Unmodified