ADRM1 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10503-50, MB10503-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: Q16186
Host: Rabbit
Reactivity: Human
Applications: WB, IHC-F, IHC-P, ICC/IF, IP,
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Background: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation. UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 42 kDa; Observed MW: 42 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of ADRM1 in K562, Hela lysates using ADRM1 antibody., Immunocytochemistry analysis of ADRM1 in Hela using ADRM1 antibody, and DAPI, Immunohistochemistry analysis of paraffin-embedded Human breast cancer using ADRM1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Alternative Name: ARM1; ARM-1; GP110
Immunogen: A synthetic peptide of human ADRM1
Conjugate: Unconjugated
Modification: Unmodified