AF/LE Purified Anti-Human CD20 Antibody [2H7] - E-AB-F12120

AF/LE Purified Anti-Human CD20 Antibody [2H7]

Sizes: 500μg, 1mg

Catalogue Numbers: E-AB-F12120-500, E-AB-F12120-1

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD20

Target Synonym: Bp35, Leukocyte surface antigen Leu-16, MS4A1, B-lymphocyte surface antigen B1,

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Host: Mouse

Species Reactivity: Human

Application: FCM, Depletion

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Mouse IgG2b, κ

Clone No.: 2H7

UNIProt ID: P11836

Background: CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F098130

Buffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Gene ID: 931

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag

Research Use Only