AF/LE Purified Anti-Human CD28 Antibody [CD28.2] - E-AB-F11950

AF/LE Purified Anti-Human CD28 Antibody [CD28.2]

Sizes: 500μg, 1mg

Catalogue Numbers: E-AB-F11950-500, E-AB-F11950-1

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD28

Target Synonym: PAS2, MNS, HGpMiX, GYPA, GPSAT,

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Host: Mouse

Species Reactivity: Human

Application: FCM, Activ

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Mouse IgG1, κ

Clone No.: CD28.2

UNIProt ID: P10747

Background: CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F097930

Buffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Gene ID: 940

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag

Research Use Only