AF/LE Purified Anti-Human/Mouse CD44 Antibody [IM7]
Sizes: 500μg, 1mg
Catalogue Numbers: E-AB-F11000-500, E-AB-F11000-1
Citations, Manuals and MSDS Available upon request.
Abbreviation: CD44
Target Synonym: CD44 antigen, CD44, CDw44, Epican, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44, LHR, MDU2, MDU3, MIC4,
Conjugation: None (Purified antibody-Azide Free/Low endotoxin)
Host: Rat
Species Reactivity: Human,Mouse
Application: FCM,Neut
Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Isotype: Rat IgG2b, κ
Clone No.: IM7
UNIProt ID: P15379, P16070,
Background: CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
Concentration: 0.5 mg/mL
Control Catalogue Number: E-AB-F098430
Buffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Gene ID: 12505960
Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.
Shipping: Ice bag
Research Use Only