AF/LE Purified Anti-Mouse CD117/c-Kit Antibody [2B8] - E-AB-F10920

AF/LE Purified Anti-Mouse CD117/c-Kit Antibody [2B8]

Sizes: 500μg, 1mg

Catalogue Numbers: E-AB-F10920-500, E-AB-F10920-1

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD117/c-Kit

Target Synonym: Mast/stem cell growth factor receptor Kit, Kit, SCFR, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, CD117,

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Host: Rat

Species Reactivity: Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Rat IgG2b, κ

Clone No.: 2B8

UNIProt ID: P05532

Background: CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F098430

Buffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Gene ID: 16590

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag

Research Use Only