AFF4 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS71968-50, BS71968-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9UHB7
Host: Rabbit
Reactivity: Human, Mouse
Applications: WB
All Applications: WB 1:500 - 1:2000
Background: The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23).
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: AFF4 polyclonal antibody detects endogenous levels of AFF4 protein.
Bioworld Molecular Weight: 150kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western Blot analysis of extracts of various cell lines, using AFF4 antibody at 1:1000 dilution.
Alternative Name: AF5Q31; CHOPS; MCEF
Immunogen: Recombinant protein of human AFF4
Conjugate: Unconjugated
Modification: Unmodified