AFP Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS71768-50, BS71768-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P02771
Host: Rabbit
Reactivity: Mouse, Rat
Applications: WB, IF
All Applications: WB 1:500 - 1:2000 IF 1:50 - 1:200
Background: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: AFP polyclonal antibody detects endogenous levels of AFP protein.
Bioworld Molecular Weight: ~ 68 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western Blot analysis of extracts of various cell lines, using AFP antibody.
Alternative Name: AFPD; FETA; HPAFP
Immunogen: Recombinant protein of human AFP
Conjugate: Unconjugated
Modification: Unmodified