AGRIN Polyclonal Antibody - BT-AP14147

AGRIN Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14147-20, BT-AP14147-50, BT-AP14147-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ)| as identified in mouse knock-out studies. The encoded protein contains several laminin G| Kazal type serine protease inhibitor| and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles| a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Areas: Neuroscience

Target Protein: AGRN

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Agrin

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O00468; Mouse: A2ASQ1; Rat: P25304

Synonyms: Agrin

GeneID: Human: 375790

Research Use Only