Product Description

AGT2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14152-20, BT-AP14152-50, BT-AP14152-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in this gene affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants.

Research Areas: Signal transduction; Metabolism

Target Protein: AGXT2

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Alanine--glyoxylate aminotransferase 2, mitochondrial

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9BYV1; Mouse: Q3UEG6; Rat: Q64565

Synonyms: Alanine--glyoxylate aminotransferase 2, mitochondrial;AGT 2;EC 2.6.1.44;;R-3-amino-2-methylpropionate--pyruvate transaminase;EC 2.6.1.40;Beta-ALAAT II;Beta-alanine-pyruvate aminotransferas

GeneID: Human: 64902

Research Use Only