AHR rabbit pAb - ES18432

AHR rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES18432-50, ES18432-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015],

Source: Rabbit

Applications: WB; IF

Dilution: WB 1:500-2000; IF/ICC 1:100-500

Reactivity: Human; Mouse; Rat; Fish

Immunogen: Synthesized peptide derived from human AHR AA range: 408-458

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 196

Human SWISS Prot NO: P35869

Subcellular Location: Cytoplasm. Nucleus. Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus.

Research Use Only