AID rabbit pAb - ES4296

AID rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4296-50, ES4296-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009],

Alternate Name: AICDA; AID; Activation-induced cytidine deaminase; Cytidine aminohydrolase

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human AICDA. AA range:81-130

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 24kD

Human Gene ID: 57379

Human SWISS Prot NO: Q9GZX7

Subcellular Location: Nucleus. Cytoplasm. Predominantly cytoplasmic (PubMed:21385873). In the presence of MCM3AP/GANP, relocalizes to the nucleus (By similarity).

Research Use Only