AIP4 (phospho Tyr420) Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA21735-50, RA21735-100
Citations, Manuals and MSDS Available upon request.
Background: itchy E3 ubiquitin protein ligase (ITCH) Homo sapiens This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Alternative Names: ITCH; E3 ubiquitin-protein ligase Itchy homolog; Itch; Atrophin-1-interacting protein 4; AIP4; NFE2-associated polypeptide 1; NAPP1
Applications: IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 83737
SWISS: Q96J02
Source: Rabbit
Research Use Only