AK1C4 Polyclonal Antibody - BT-AP06132

AK1C4 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06132-20, BT-AP06132-50, BT-AP06132-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Research Areas: Cancer; Metabolism; Signal transduction

Target Protein: AKR1C4

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Aldo-keto reductase family 1 member C4

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P17516

Synonyms: Aldo-keto reductase family 1 member C4;EC 1.1.1.-;3-alpha-HSD1;3-alpha-hydroxysteroid dehydrogenase type I;EC 1.1.1.50;Chlordecone reductase;CDR;EC 1.1.1.225;Dihydrodiol dehydrogenase 4

GeneID: Human: 1109

Research Use Only