AK4 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS6519-50, BS6519-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P27144
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC, IF
All Applications: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Background: Adenylate kinases 1-5 (designated AK1-5) are a set of enzymes that regulate the phosphorylation state of intracellular adenine nucleotides, which are the principle high-energy phosphoryl-carrying molecules in living cells. AKs influence metabolic signals, which include gene expression, ion channel activity and protein kinase-mediated signaling, by catalyzing phosphoryl transfer between adenine nucleotides (AMP, ADP, ATP). Inherited mutations leading to AK deficiencies in erythrocytes have been implicated in hemolytic anemia. Rat AK4 mRNA is expressed as a 223 amino acid protein in the central nervous system from the middle stage of embryogenesis to adulthood.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: AK4 polyclonal antibody detects endogenous levels of AK4 protein.
Bioworld Molecular Weight: ~ 25 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of AK4 polyclonal antibody, Immunoprecipitation analysis of 200ug extracts of HepG2 cells, using 3 ug AK4 antibody., Immunofluorescence analysis of A549 cells, using AK4 polyclonal antibody
Alternative Name: Adenylate kinase 3 like 1; Adenylate kinase 3-like; adenylate kinase 4; Adenylate kinase isoenzyme 4; mitochondrial; AK3; AK3L1; AK3L2; AK4; ATP-AMP transphosphorylase; GTP:AMP phosphotransferase; KAD4; MGC166959; mitochondrial adenylate kinase 3; nucleoside-triphosphate adenylate kinase;
Immunogen: Recombinant full length Human AK4.
Conjugate: Unconjugated
Modification: Unmodified