AKAP12 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-12884-60, E-AB-12884-120, E-AB-12884-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: AKAP12
Target Synonym: A kinase (PRKA) anchor protein (gravin) 12; A kinase Anchor Protein 12; A kinase anchor protein 250kDa; A-kinase anchor protein 12; A-kinase anchor protein 250 kDa; AKA12; AKAP 12; AKAP 250; AKAP-12; Akap12; AKAP250; DKFZp686M0430; DKFZp686O0331; FLJ20945; FLJ97621; Gercelin; Gravin; Kinase scaffold protein gravin; Myasthenia gravis autoantigen; Myasthenia gravis autoantigen gravin; OTTHUMP00000017426; OTTHUMP00000017427; Src-Suppressed C Kinase Substrate; Srcs5; SSeCKS; Tsga12
Research Areas: Cancer, Neuroscience, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q02952
Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Concentration: 0.4 mg/mL
Immunogen: Synthetic peptide of human AKAP12
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only